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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cbf09c164a296837845de582f79f44fbdbb020acbb385b4df42baee5378b8d7' 
  AND token = 'RZ1fXSNN4AgyETSpLx4NSx4AmlIxtgVzi0+VjdyfROk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}