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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63732a523cba17709193dabc73627f313f4b331f9c801609ac20c9db32504769' 
  AND token = 'mUF49depz5PC3sPqAG5vkjkG2RlH3v2W7hmzihGhWaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}