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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6436e179dee65e9fb0cbc7225475cdcab028f1bca9bbfb532f816c93e0a995b2' 
  AND token = '+DO1hvKIyY5MT2Ssf6HR0BvkT9SRJ3MVsbTnWwTSTZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}