SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa957a3fbf2340e00a9aa78f59a6eedd8872493455a670781c82c27b8e2b7f3e' 
  AND token = 'oHh2/6vQH7TqpFRMGskjZp33HLSWMH+rzpeZbqHfe8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}