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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549af8dbde22c77643d5bcad0beb7f60b975486836c5d6433cfa7596ab70ee52' 
  AND token = '01DCeaw70a3gnjzRXTXqJwlgpN5hJmjIN9bWGwe3SqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}