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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9abecce53ea01dd558244e69780ea2cc275dfab465dc0f1ce3e6a9b2b175628' 
  AND token = 'nqQ3ytxwhlj4qWFI9VvtEzroNUX5HhTw9xtluwMv9mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}