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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb192022450e37c7bb59e37f86fc47327189b810a39f8b8b3a25b55a28f286bb' 
  AND token = 'kXrQxBDsAVZriQLNi/QnIfLySBy+uGdejTCkbY47FP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}