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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c8a061f0c0501d734a3f7d16d4daeab3e3139cdaf0f81b0b302960384c18081' 
  AND token = '3Ux9JthyprO4pjoq8msOuvu/VW4NZtT4TyBkcapLaSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}