SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f8d448a4c8e23583fd09891065c7b9969b19f6df997580a1ff329187e529af8' 
  AND token = 'URP7sxRudUfB+R50PkcC4T/8+xWL0AW+gSjbXVeZsWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}