SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd403675753c28c2c9c00468e90d6014fa1cd59ef596f24cc692c4d1edd09bcde' 
  AND token = 'JGNZlHSsJNTrXsvw3Yv0bbYjDQyDmjFFZBoCdbC26gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}