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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708aea0f025d99e8fec9d6c9f85b22562ff2b4544be185089e5a3fe2c8c3f3d3' 
  AND token = 'mERkx802fKtGfDU+lgxIg2zUb6iEEM2QE3Dpcch5Xjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}