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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1d73d4a80ab76ce63655911b0c930ebc7030c961f93ac66225d953915c1778' 
  AND token = 'gBvEt3kZRPt2YKCjvDikCsldxWRlslpGgy3N2tZ1oZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}