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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '248bd441233b27f0af3fb8a967b3e4e03400869425c01e9a4ee3a76664dcef07' 
  AND token = 'aLqSt+TQgmmNFsUJzMIJ88F2jYWlUDMU0ztRW7kPqxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}