SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ba0e6ce98b51f4ea6defc44c234d7fb123f7218f17563a99e0600306ff54d6' 
  AND token = '6X2ekk+0sjx90AeWePGYuSRAioNftDulTUFBFsypeZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}