SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80fdd69a6d1dd6ede430212dea394650898f37f5f9d130a940c3e98ef7026c7e' 
  AND token = '1gRwnTMVbE7myyjmvHzpnrTdJU9Hyv8jpfvIrRHXZqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}