SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd40d41558f3b3d1a70b5a2e46ed343fa3de34545110756bfb89f4af75d964d' 
  AND token = 'GJNVX6uQNuDvgvNcYCm3prCZow1EtgHqIugFW9C08jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}