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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb158ef21bd926162d64f049fb4bc6eb95d3e393ee0d7098019c958f365401aa' 
  AND token = '+C0sRpp5W0Ifru9sBY1SpgZ4vSdFSU//vP/CDw9Mc0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}