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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '428fa9f17a40616b985c3a4c432ae9c23f4b8de0a0f83a91e270016638c8e4fc' 
  AND token = '/v56unnUvY5BeevlXAz5deBZh1BLGvV6C2vwF2viVI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}