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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0338b988f18ca8efb61b9870b1ab2900fa55d8a52d6c982f5e6770fb2775299' 
  AND token = 'ykFdX33le5kYD0zm7RX42BWK1MtqGkrjyLiqCtnGhpY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}