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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45445373f3f8435444924c8e8376d1817f0939179241d17b1996eb8cb612886a' 
  AND token = '+/Y3mnDYFgUxhB1u/bc48vJWPsjEeFFdvo9ycMYRbyA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}