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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0804c399925d64021902a87c52637aed2036e5c6de18a818cd809169d3a95a1' 
  AND token = 't1AooJL3DWLyIjt+IxhEn1ES2ySTE4aOA0j4VNbM9y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}