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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe49925ee7b84efedb06cce0d0440856195c1daf08fe0f20ab6d001431a684f' 
  AND token = '25EZBiq8Mp1ynz6/0lgNShJjxcVb2JDmX7AI1qSKxaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}