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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '533650aa8775cdae61e32ae2f7cc45cd6048d5bfba09c84cc790d409c2f93960' 
  AND token = 'ERjjRhxyaHx+wp3TA9WABCWximqiYM7CI9HaNq2mtps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}