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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36e2e5f2b08e581cd73685fe2f4008d4eae7d3ec5a121bcd255f43e1f94c0158' 
  AND token = 'ErHaB6NXsr0HTKJVBl7lXTL1wFgPCyTC0rsAvjJFTSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}