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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '278fc7f5f490dbae7ad095c41a633967fb6bb761f6b71c4559f60ae3ffc22d5b' 
  AND token = 'INOflv27BvNb0MxXBS3ve8/09PV45tSfOX1gUoIONws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}