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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29f674771f9f53ac8008e0f7adde8c7e71f532d4d0320a1b2aa963a7a47d5e5d' 
  AND token = 'fiwbOHXdIaeSI4+j+KYy2dPmq5y3NJVRZzeNxkX+HhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}