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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ee580cdd8ea22b0c0cc3a78f762918fa266aefa1605a72472f55571f3b825be' 
  AND token = 'gtszGukQE1TvmrX6+/l5MwCYkBA87pxHLg3r1XtHPkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}