SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3c3c65a577ea637f0fa2fe25cd0011f841fa4e4fc61ae159353084200a1050a' 
  AND token = 'LfS0gwD7W+ttb4PDriheH8zQkqQ+9xWHSKyLk4HmyPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}