SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be1981c5905417d23dca2b010ad32ab4cd7cfd65360c7536205634ccf34c149' 
  AND token = 'yeo97YalDLRhlPGFDgSbqNtgGV4H8FL2IA9nOX+rkWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}