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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f1b2fc9da045aaaf20f6a81ef53212fa6b874cac05cc12bdad98df0a15d0284' 
  AND token = 'JsRG5G58IveCImVAtOlfR3atbzqPBC4Mr14nGoNKK64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}