SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60c5a96597b3b28a35db0dc1eb7cfaf0782fbb16c6aa7cdcd43c19eabc563778' 
  AND token = 'arUS1dD5dTiY4abAVEdgjJbc7A9PIup6nc66rfI5XT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}