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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72b1475865cd3a75714a694c532c6576999ef9b946ed40b1e6e7050cb1ff831b' 
  AND token = 'LvnmWfFJKWILk+WN4CIhjfDmc1NQpdv64XnDuHquOCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}