SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e64f998b36bdd443023e731b05e03017bcad7a3154a4e80e065faabcdbaed003' 
  AND token = 'pmC4xOB8MF/sdRoSAmzqShi0G6MUh/nfsIl+bNTDhvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}