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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e12f7c4072967068c65915a4c699274dc836ecd75624fcefe417b921b7f05f11' 
  AND token = 'oowJ6iHTZxxbTuX2fu3FI2mUCZ4zB8G2cAx51xzcFxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}