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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '110fcbf728136382f6328a439e822e88c56da1e1fa354596adcf7945427662cb' 
  AND token = 'aNinAiw9vIeZq2qIA9IC5f+IHVpk8DfLpfIepiq1FM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}