SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1e0b9b30d08733f3345ea088dc505eb007046b19d20bb6c2dd87a915c5573f' 
  AND token = 'iVcT7RpyTUSuEGjFCNnEUGPE+GjJR13mSruCwBbCkY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}