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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5a1e108cd60dcd0f35fd903925a6c6e2f1c42ecee136c14ef232f5853db339' 
  AND token = 'TluTdvizPVbcec//YKC905eMLnF0OBfcDkd3Sisq02U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}