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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5868fa4ef75ea29b0ac25157562c4cf40b98008b99ebdd864a39f82ab2f2d10c' 
  AND token = 'emYISXg23I9HwZPxnQhk4Vt9rkLXOvrN/psp+dHTYHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}