SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5826203eb4ad36e80f19e6e2097839cfc59165058d345f33cebc60e45a917829' 
  AND token = 'YFMe7ZnwMqldQmVF+y7cqXDO1EkRj7w6QfmGrYnz0qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}