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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e7898378494938b6d090a6591f0859336f1de61d6fa1522d283eb0900e1432' 
  AND token = 'D7AHU3UfTLPMlUHwwywdlM8lzdmgjUjfo2EUB1116rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}