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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da615ca75b3bf5b98956a53fe1326fac6038fdb0bf9fd1abdb2d0ea8016a5ec' 
  AND token = 'W2JNPv7ULz2EtW/feS+7Q7ZAljz0aVHF0IecdLdrV/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}