SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88ce289edb4401cb2c9b65f679c8618ad45beeb35a8c3491f3592ad99c54fc20' 
  AND token = 'c2Mrjp89cxgs4pClyJaTVHOg6toKtHONAI5UNSQmQew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}