SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '02a45c9cd3c3be3b915fdd18cb56fb3ebd60a2ee43c69cf80f1009153dfac639' 
  AND token = 'FfSugVZ2GknNKzKw8mnxDP5W324mZyho5bho9zT4H/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}