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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7a5937205e3634647a9b7367cd8441e29b9957a825bdffea8e4f06d710cdf20' 
  AND token = 'QLL73/GQ6N5MeUz1comi9sSLxc589EjXqATfEZjVAug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}