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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '921d2a7a811ddd6e11f751f8d4f13f76af086ca85b2d51691c55714c0a9f8abd' 
  AND token = 'ttWpAX4uyy2d/h4WSwjDdRf4BjLFyxPBZO8YteKzPsU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}