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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f572f7b381f113093c6076b542d05a18a6e650f09a925c1b183795e60cb1c27' 
  AND token = '75MT5UX8KJA5f5xcZ+GuQROAOYWEz/RO0YfzKgLgzqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}