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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a6396470dd7d4627282fad4b8a1647404ba9c8b41584952c4d00eac888bc9c8' 
  AND token = 'gVy0B/OEjB1t5tn8sQFiQixMJsUhgFKXd0p4+qsQXfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}