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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52592bc61279b16a5eab4fe3f082f641521665fd6ecd1d3b0e1f80c37baf5cf5' 
  AND token = '0NnON9DtIm8PudyU0+WGRmLbbwjoxMGD+a3g5e6KtL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}