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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a0648945eb061b7f504b672f7b0d072be9ff4339a6809957ca1c4aeaf0e4190' 
  AND token = '3g6cGiA4r20aAK5ZnElQHH0PWQO8MdOjLfGXB8wOu9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}