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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d7b4eacf33baf3dd8a281f4da7a0adcf2e5efd993cd5096f8da34098c8a223c' 
  AND token = 'sm0/e+qIS8HxStCW5fP7BbEQe25STh+rM2W6XAuRFY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}